H-Thr(tBu)-OH
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O-tert-Butyl-L-threonine (H-Thr(tBu)-OH) is a protected form of L-threonine commonly used in solid-phase peptide synthesis. It features a tert-butyl group that shields the hydroxyl side chain, preventing unwanted side reactions during coupling. This derivative ensures high purity and stability under standard peptide synthesis conditions.
- CAS No.: 4378-13-6
- Molecular Formula: C₈H₁₇NO₃
- Purity: 99% min
- Appearance White solid
- Molecular Weight 175.23 g/mol
- Density 1.1±0.1 g/cm³
- Boiling Point 275.3±30.0 °C at 760 mmHg
- Melting Point 244–247 °C
- Flash Point 120.3±24.6 °C
- Packaging 25kg/fibre drum
- Storage Conditions Keep in dark place, inert atmosphere, room temperature
- Customs Code 29241990
- Production capacity 1 ton/month
- Product Name
- O-tert-Butyl-L-threonine;
- H-Thr(tBu)-OH;
- (2S,3R)-2-Amino-3-(tert-butoxy)butanoic acid;
- L-Threonine, O-(1,1-dimethylethyl)-;
- (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoic acid;
- O-t-Butyl-L-threonine;
- (2S,3R)-2-amino-3-tert-butoxybutanoic acid;
- O-tert-Butyl-L-allo-threonine;
- (2S,3R)-2-azaniumyl-3-[(2-methylpropan-2-yl)oxy]butanoate
- Applications Raw material for GLP-1 peptide synthesis and polypeptides

